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Harold Varmus, M.D. former Director of the National Institutes of Health and co-recipient of a Nobel Prize for studies of the genetic basis of cancer, has served as the President and Chief Executive Officer of Memorial Sloan-Kettering Cancer Center in New York City since January 2000.
Much of Dr. Varmus’ scientific work was conducted during 23 years as a faculty member at the University of California, San Francisco, where he and Dr. J. Michael Bishop and their co-workers demonstrated the cellular origins of the oncogene of a chicken retrovirus. This discovery led to the isolation of many cellular genes that normally control growth and development and are frequently mutated in human cancer. For this work, Bishop and Varmus received many awards, including the 1989 Nobel Prize for Physiology or Medicine. Varmus is also widely recognized for his studies of the replication cycles of retroviruses and hepatitis B viruses, the functions of genes implicated in cancer, and the development of mouse models for human cancer (the focus of much of the current work in his laboratory at Memorial Sloan-Kettering Cancer Center).
In 1993, Varmus was named by President Clinton to serve as the Director of the National Institutes of Health, a position he held until the end of 1999. During his tenure at the NIH, he initiated many changes in the conduct of intramural and extramural research programs, recruited new leaders for most of the important positions at the NIH, planned three major buildings on the NIH campus, and helped to increase the NIH budget from under $11 billion to nearly $18 billion.
He is a graduate of Columbia University’s College of Physicians and Surgeons, worked as a medical student in a hospital in India, and served on the medical house staff at Columbia-Presbyterian Hospital.
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